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ahr antagonist ch 223191  (MedChemExpress)


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    Structured Review

    MedChemExpress ahr antagonist ch 223191
    Ahr Antagonist Ch 223191, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 149 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ahr+antagonist+ch+223191/CH-223191/pmc13397888-65-11-14
    Average 98 stars, based on 149 article reviews
    ahr antagonist ch 223191 - by Bioz Stars, 2026-09
    98/100 stars

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    Related Articles

    Concentration Assay:

    Article Title: Antimalarial Drug Artemotil Promotes Induction of Type 1 Regulatory T Cells.
    Article Snippet: Artemisinin and its derivatives, used as front-line anti-malarial drugs, exhibit anti-inflammatory properties.. They were found to suppress the generation and function of Th1 and Th17 cells while promoting the generation of Foxp3 + regulatory T cells (Tregs).. However, the specific role of Artemotil (β-arteether) in modulating the generation and functions of CD4 + T cells, particularly Type 1 regulatory T cells (Tr1), remains to be explored.

    Blocking Assay:

    Article Title: Lactobacillus johnsonii Alleviates Immune Checkpoint Inhibitor-Associated Colitis by Modulating Macrophage Polarization, Th1/Treg Cell Balance, and Intestinal Barrier Function via the Tryptophan Metabolism-AhR Pathway
    Article Snippet: .. − For the mouse aryl hydrocarbon receptor (AhR) blocking experiment, the AhR antagonist CH-223191 (MedChemExpress, HY-12684, New Jersey, America) was administered to mice via intraperitoneal injection at 10 mg/kg every 2 days, beginning simultaneously with L. johnsonii gavage. ..

    Injection:

    Article Title: Lactobacillus johnsonii Alleviates Immune Checkpoint Inhibitor-Associated Colitis by Modulating Macrophage Polarization, Th1/Treg Cell Balance, and Intestinal Barrier Function via the Tryptophan Metabolism-AhR Pathway
    Article Snippet: .. − For the mouse aryl hydrocarbon receptor (AhR) blocking experiment, the AhR antagonist CH-223191 (MedChemExpress, HY-12684, New Jersey, America) was administered to mice via intraperitoneal injection at 10 mg/kg every 2 days, beginning simultaneously with L. johnsonii gavage. ..

    Article Title: Indole-3-Lactic Acid Attenuates IMQ-Induced Psoriasiform Dermatitis in Mice via AhR-Dependent Suppression of IL-17A
    Article Snippet: For probiotic intervention, Lactobacillus reuteri DSM17938 (BioGaia) was delivered by oral gavage at 1.0 × 10 8 CFU per day, starting 2 weeks prior to IMQ treatment and maintained throughout the experiment. .. Where indicated, the AhR antagonist CH-223191 (MedChemExpress) was given by intraperitoneal injection at 10 mg kg −1 day −1 , commencing 2 days before and continuing during IMQ exposure. ..

    Article Title: Indole-3-Lactic Acid Attenuates IMQ-Induced Psoriasiform Dermatitis in Mice via AhR-Dependent Suppression of IL-17A
    Article Snippet: For probiotic intervention, Lactobacillus reuteri DSM17938 (BioGaia) was delivered by oral gavage at 1.0 × 108 CFU per day, starting 2 weeks prior to IMQ treatment and maintained throughout the experiment. .. Where indicated, the AhR antagonist CH-223191 (MedChemExpress) was given by intraperitoneal injection at 10 mg kg−1 day−1, commencing 2 days before and continuing during IMQ exposure. ..

    Recombinant:

    Article Title: Benvitimod Inhibits IL-4- and IL-13-Induced Tight Junction Impairment by Activating AHR/ARNT Pathway and Inhibiting STAT6 Phosphorylation in Human Keratinocytes.
    Article Snippet: Tight junctions are involved in skin barrier functions.. In this study, the expression of CLDN1, CLDN4, and OCLN was found to decrease in skin lesions of atopic dermatitis by bioinformatics analysis.. Immunohistochemistry staining in skin specimens from 12 patients with atopic dermatitis and 12 healthy controls also showed decreased CLDN1, CLDN4, and OCLN expression in atopic dermatitis lesions.



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    ahr antagonist ch 223191  (MedChemExpress)
    98
    MedChemExpress ahr antagonist ch 223191
    Ahr Antagonist Ch 223191, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ahr+antagonist+ch+223191/CH-223191/pmc13397888-65-11-14
    Average 98 stars, based on 1 article reviews
    ahr antagonist ch 223191 - by Bioz Stars, 2026-09
    98/100 stars
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    ahr antagonist pretreatment  (MedChemExpress)
    98
    MedChemExpress ahr antagonist pretreatment
    (A) Mice were orally infected with 500 TsML, followed by oral administration of vehicle control or L. murinus (1 × 10^9 CFU/mL) from 1 to 14 dpi, and at 14 dpi, adult worms were recovered from each group to assess the burden of T. spiralis (n=6). (B-D) In vivo effects in antibiotic-treated mice. Western blot analysis and quantification of AhR and Cyp1a1 protein levels in the duodenum after supplementation with vehicle, L. murinus (1×10 9 CFU/mL ) for 7days (n=3). (E-L) Flow cytometric analysis of Treg (CD4 + CD25 + Foxp3 + ) and Th17 (CD4 + IL-17A + ) cells in mesenteric lymph nodes (E, F, G and H) and spleen (I, J, K and L) after supplementation with vehicle, L. murinus (1×10 9 CFU/mL) for 7days after 21 days of antibiotic <t>pretreatment</t> (n=5). (M) Mice were orally infected with 500 TsML, followed by oral administration of vehicle control or ILA (20 mg/kg) from 1 to 14 dpi, and at 14 dpi, adult worms were recovered from each group to assess the burden of T. spiralis (n=6). (N-P) In vivo effects in antibiotic-treated mice. (N-P) Western blot analysis and quantification of AhR and Cyp1a1 protein levels in the duodenum after supplementation with vehicle, ILA (20 mg/kg) for 7days (n=3). (Q-X) Flow cytometric analysis of Treg (CD4 + CD25 + Foxp3 + ) and Th17 (CD4 + IL-17A + ) cells in mesenteric lymph nodes (Q, R, S and T) and spleen (U, V, W and X) after supplementation with vehicle, ILA (20 mg/kg) for 7days after 21 days of antibiotic pretreatment (n=5). (Y) Representative immunofluorescence images confirming increased AhR and Cyp1a1 protein in organoids treated with L. murinus (1×10 6 CFU/mL) or ILA (2 mM) for 48 h. Data are representative of three independent experiments. Data are presented as mean ± SD and were analyzed by Student’s t-test (A, C, D, F, H, J, L, M, O, P, R, T, V, and X). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
    Ahr Antagonist Pretreatment, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ahr+antagonist+ch+223191/CH-223191/bio_rxiv__64898__2026__05__06__723221-210-2-15
    Average 98 stars, based on 1 article reviews
    ahr antagonist pretreatment - by Bioz Stars, 2026-09
    98/100 stars
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    ahr antagonist ch 223 191  (MedChemExpress)
    98
    MedChemExpress ahr antagonist ch 223 191
    (A) Mice were orally infected with 500 TsML, followed by oral administration of vehicle control or L. murinus (1 × 10^9 CFU/mL) from 1 to 14 dpi, and at 14 dpi, adult worms were recovered from each group to assess the burden of T. spiralis (n=6). (B-D) In vivo effects in antibiotic-treated mice. Western blot analysis and quantification of AhR and Cyp1a1 protein levels in the duodenum after supplementation with vehicle, L. murinus (1×10 9 CFU/mL ) for 7days (n=3). (E-L) Flow cytometric analysis of Treg (CD4 + CD25 + Foxp3 + ) and Th17 (CD4 + IL-17A + ) cells in mesenteric lymph nodes (E, F, G and H) and spleen (I, J, K and L) after supplementation with vehicle, L. murinus (1×10 9 CFU/mL) for 7days after 21 days of antibiotic <t>pretreatment</t> (n=5). (M) Mice were orally infected with 500 TsML, followed by oral administration of vehicle control or ILA (20 mg/kg) from 1 to 14 dpi, and at 14 dpi, adult worms were recovered from each group to assess the burden of T. spiralis (n=6). (N-P) In vivo effects in antibiotic-treated mice. (N-P) Western blot analysis and quantification of AhR and Cyp1a1 protein levels in the duodenum after supplementation with vehicle, ILA (20 mg/kg) for 7days (n=3). (Q-X) Flow cytometric analysis of Treg (CD4 + CD25 + Foxp3 + ) and Th17 (CD4 + IL-17A + ) cells in mesenteric lymph nodes (Q, R, S and T) and spleen (U, V, W and X) after supplementation with vehicle, ILA (20 mg/kg) for 7days after 21 days of antibiotic pretreatment (n=5). (Y) Representative immunofluorescence images confirming increased AhR and Cyp1a1 protein in organoids treated with L. murinus (1×10 6 CFU/mL) or ILA (2 mM) for 48 h. Data are representative of three independent experiments. Data are presented as mean ± SD and were analyzed by Student’s t-test (A, C, D, F, H, J, L, M, O, P, R, T, V, and X). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
    Ahr Antagonist Ch 223 191, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ahr+antagonist+ch+223191/CH-223191/pm41886955-146-11-16
    Average 98 stars, based on 1 article reviews
    ahr antagonist ch 223 191 - by Bioz Stars, 2026-09
    98/100 stars
    		  Buy from Supplier
    ahr antagonist ch223191  (MedChemExpress)
    98
    MedChemExpress ahr antagonist ch223191
    (A) Mice were orally infected with 500 TsML, followed by oral administration of vehicle control or L. murinus (1 × 10^9 CFU/mL) from 1 to 14 dpi, and at 14 dpi, adult worms were recovered from each group to assess the burden of T. spiralis (n=6). (B-D) In vivo effects in antibiotic-treated mice. Western blot analysis and quantification of AhR and Cyp1a1 protein levels in the duodenum after supplementation with vehicle, L. murinus (1×10 9 CFU/mL ) for 7days (n=3). (E-L) Flow cytometric analysis of Treg (CD4 + CD25 + Foxp3 + ) and Th17 (CD4 + IL-17A + ) cells in mesenteric lymph nodes (E, F, G and H) and spleen (I, J, K and L) after supplementation with vehicle, L. murinus (1×10 9 CFU/mL) for 7days after 21 days of antibiotic <t>pretreatment</t> (n=5). (M) Mice were orally infected with 500 TsML, followed by oral administration of vehicle control or ILA (20 mg/kg) from 1 to 14 dpi, and at 14 dpi, adult worms were recovered from each group to assess the burden of T. spiralis (n=6). (N-P) In vivo effects in antibiotic-treated mice. (N-P) Western blot analysis and quantification of AhR and Cyp1a1 protein levels in the duodenum after supplementation with vehicle, ILA (20 mg/kg) for 7days (n=3). (Q-X) Flow cytometric analysis of Treg (CD4 + CD25 + Foxp3 + ) and Th17 (CD4 + IL-17A + ) cells in mesenteric lymph nodes (Q, R, S and T) and spleen (U, V, W and X) after supplementation with vehicle, ILA (20 mg/kg) for 7days after 21 days of antibiotic pretreatment (n=5). (Y) Representative immunofluorescence images confirming increased AhR and Cyp1a1 protein in organoids treated with L. murinus (1×10 6 CFU/mL) or ILA (2 mM) for 48 h. Data are representative of three independent experiments. Data are presented as mean ± SD and were analyzed by Student’s t-test (A, C, D, F, H, J, L, M, O, P, R, T, V, and X). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
    Ahr Antagonist Ch223191, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ahr+antagonist+ch+223191/CH-223191/pm41687337-84-1-4
    Average 98 stars, based on 1 article reviews
    ahr antagonist ch223191 - by Bioz Stars, 2026-09
    98/100 stars
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    ahr antagonist ch223191 concentration  (Selleck Chemicals)
    94
    Selleck Chemicals ahr antagonist ch223191 concentration
    (A) Mice were orally infected with 500 TsML, followed by oral administration of vehicle control or L. murinus (1 × 10^9 CFU/mL) from 1 to 14 dpi, and at 14 dpi, adult worms were recovered from each group to assess the burden of T. spiralis (n=6). (B-D) In vivo effects in antibiotic-treated mice. Western blot analysis and quantification of AhR and Cyp1a1 protein levels in the duodenum after supplementation with vehicle, L. murinus (1×10 9 CFU/mL ) for 7days (n=3). (E-L) Flow cytometric analysis of Treg (CD4 + CD25 + Foxp3 + ) and Th17 (CD4 + IL-17A + ) cells in mesenteric lymph nodes (E, F, G and H) and spleen (I, J, K and L) after supplementation with vehicle, L. murinus (1×10 9 CFU/mL) for 7days after 21 days of antibiotic <t>pretreatment</t> (n=5). (M) Mice were orally infected with 500 TsML, followed by oral administration of vehicle control or ILA (20 mg/kg) from 1 to 14 dpi, and at 14 dpi, adult worms were recovered from each group to assess the burden of T. spiralis (n=6). (N-P) In vivo effects in antibiotic-treated mice. (N-P) Western blot analysis and quantification of AhR and Cyp1a1 protein levels in the duodenum after supplementation with vehicle, ILA (20 mg/kg) for 7days (n=3). (Q-X) Flow cytometric analysis of Treg (CD4 + CD25 + Foxp3 + ) and Th17 (CD4 + IL-17A + ) cells in mesenteric lymph nodes (Q, R, S and T) and spleen (U, V, W and X) after supplementation with vehicle, ILA (20 mg/kg) for 7days after 21 days of antibiotic pretreatment (n=5). (Y) Representative immunofluorescence images confirming increased AhR and Cyp1a1 protein in organoids treated with L. murinus (1×10 6 CFU/mL) or ILA (2 mM) for 48 h. Data are representative of three independent experiments. Data are presented as mean ± SD and were analyzed by Student’s t-test (A, C, D, F, H, J, L, M, O, P, R, T, V, and X). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
    Ahr Antagonist Ch223191 Concentration, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ahr+antagonist+ch+223191/CH-223191/pm41430399-226-1-8
    Average 94 stars, based on 1 article reviews
    ahr antagonist ch223191 concentration - by Bioz Stars, 2026-09
    94/100 stars
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    Image Search Results


    (A) Mice were orally infected with 500 TsML, followed by oral administration of vehicle control or L. murinus (1 × 10^9 CFU/mL) from 1 to 14 dpi, and at 14 dpi, adult worms were recovered from each group to assess the burden of T. spiralis (n=6). (B-D) In vivo effects in antibiotic-treated mice. Western blot analysis and quantification of AhR and Cyp1a1 protein levels in the duodenum after supplementation with vehicle, L. murinus (1×10 9 CFU/mL ) for 7days (n=3). (E-L) Flow cytometric analysis of Treg (CD4 + CD25 + Foxp3 + ) and Th17 (CD4 + IL-17A + ) cells in mesenteric lymph nodes (E, F, G and H) and spleen (I, J, K and L) after supplementation with vehicle, L. murinus (1×10 9 CFU/mL) for 7days after 21 days of antibiotic pretreatment (n=5). (M) Mice were orally infected with 500 TsML, followed by oral administration of vehicle control or ILA (20 mg/kg) from 1 to 14 dpi, and at 14 dpi, adult worms were recovered from each group to assess the burden of T. spiralis (n=6). (N-P) In vivo effects in antibiotic-treated mice. (N-P) Western blot analysis and quantification of AhR and Cyp1a1 protein levels in the duodenum after supplementation with vehicle, ILA (20 mg/kg) for 7days (n=3). (Q-X) Flow cytometric analysis of Treg (CD4 + CD25 + Foxp3 + ) and Th17 (CD4 + IL-17A + ) cells in mesenteric lymph nodes (Q, R, S and T) and spleen (U, V, W and X) after supplementation with vehicle, ILA (20 mg/kg) for 7days after 21 days of antibiotic pretreatment (n=5). (Y) Representative immunofluorescence images confirming increased AhR and Cyp1a1 protein in organoids treated with L. murinus (1×10 6 CFU/mL) or ILA (2 mM) for 48 h. Data are representative of three independent experiments. Data are presented as mean ± SD and were analyzed by Student’s t-test (A, C, D, F, H, J, L, M, O, P, R, T, V, and X). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

    Journal: bioRxiv

    Article Title: Helminth-remodeled microbial indole-3-lactic acid drives AhR-dependent disease tolerance

    doi: 10.64898/2026.05.06.723221

    Figure Lengend Snippet: (A) Mice were orally infected with 500 TsML, followed by oral administration of vehicle control or L. murinus (1 × 10^9 CFU/mL) from 1 to 14 dpi, and at 14 dpi, adult worms were recovered from each group to assess the burden of T. spiralis (n=6). (B-D) In vivo effects in antibiotic-treated mice. Western blot analysis and quantification of AhR and Cyp1a1 protein levels in the duodenum after supplementation with vehicle, L. murinus (1×10 9 CFU/mL ) for 7days (n=3). (E-L) Flow cytometric analysis of Treg (CD4 + CD25 + Foxp3 + ) and Th17 (CD4 + IL-17A + ) cells in mesenteric lymph nodes (E, F, G and H) and spleen (I, J, K and L) after supplementation with vehicle, L. murinus (1×10 9 CFU/mL) for 7days after 21 days of antibiotic pretreatment (n=5). (M) Mice were orally infected with 500 TsML, followed by oral administration of vehicle control or ILA (20 mg/kg) from 1 to 14 dpi, and at 14 dpi, adult worms were recovered from each group to assess the burden of T. spiralis (n=6). (N-P) In vivo effects in antibiotic-treated mice. (N-P) Western blot analysis and quantification of AhR and Cyp1a1 protein levels in the duodenum after supplementation with vehicle, ILA (20 mg/kg) for 7days (n=3). (Q-X) Flow cytometric analysis of Treg (CD4 + CD25 + Foxp3 + ) and Th17 (CD4 + IL-17A + ) cells in mesenteric lymph nodes (Q, R, S and T) and spleen (U, V, W and X) after supplementation with vehicle, ILA (20 mg/kg) for 7days after 21 days of antibiotic pretreatment (n=5). (Y) Representative immunofluorescence images confirming increased AhR and Cyp1a1 protein in organoids treated with L. murinus (1×10 6 CFU/mL) or ILA (2 mM) for 48 h. Data are representative of three independent experiments. Data are presented as mean ± SD and were analyzed by Student’s t-test (A, C, D, F, H, J, L, M, O, P, R, T, V, and X). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

    Article Snippet: For the AhR antagonist pretreatment experiments, mice were intraperitoneally injected with 10 mg/kg of CH223191 (Med Chem Express) for 14 days while being infected with T. spiralis .

    Techniques: Infection, Control, In Vivo, Western Blot, Immunofluorescence